Clusterin Antibody / Apolipoprotein J / APO-J [Monoclonal] from NSJ Bioreagents

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Supplier Page from
NSJ Bioreagents for
Clusterin Antibody / Apolipoprotein J / APO-J [Monoclonal]

Description

Clusterin, also designated complement lysis inhibitor (CLI), apolipoprotein J (APOJ), sulfated glycoprotein 2 (SGP2), SP40 and testosterone-repressed prostate message 2 (TRPM2), is a secretory, heterodimeric glycoprotein that influences immune regulation, cell adhesion, transformation, lipid transportation, tissue remodeling, membrane recycling and cell-cell interactions. Clusterin is synthesized as a 449 amino acid polypeptide that is post-translationally cleaved at an internal bond between Arg 227 and Ser 228. Two subunits, -Amyloid structure and neuritic toxicity in vivo and may influence Alzheimer s pathogenesis